Supported by RS and GIS platform, the vectorial land use change data of Harbin, Daqing and Qiqihar, which were in the range of Ha-Da-Qi Industrial Corridor, were obtained on the basis of the remote sensing images covering 1980, 1985, 1990, 1995, 2000 and 2005. Based on economic statistical data of the three cities and the dynamic change model of land use, the land use change increment data of 2010 were predicted. Furthermore, two driving indicators (driving efficiency index and economic benefit index) were introduced to evaluate the land use change, and the relationships between land use structure and economic development in the three cities were compared. In addition, the rationality of the land use structure was analyzed. The results showed that, the land resources in Daqing damaged due to excessive exploitation of petroleum resources. At the same time, the exhaustion of oil resources led to the restriction on economic development in the city, especially from 1995 to 2005, thus the regional industries has been restructured correspondingly since 2005 in order to make the land resources and economic development in a relatively stable way. As for Harbin, the economic development was not dependent on the exploitation of land resources completely compared with Daqing city. In the major city, more factors such as government policies, foreign trade and high technology dominated its economic development. Different from the two cities analyzed above, the economic development of Qiqihar city tended to be dependent on land resources to a certain degree, hence resulting in the imbalance in the land use structure, which would inevitably affect the regional economic development in the future. So, this research provides a basis for further evaluation of land use and land use structure adjustment.